Baclofen (Baclofen Tablets) Side Effects, Interactions, Warning

6.15.2018 | Christian Lawman

Baclofen is a muscle relaxant and antispastic.

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Gastrointestinal: Nausea (4 to 12%), constipation (2 to 6%); and rarely, dry mouth, anorexia, taste disorder, abdominal pain, vomiting, diarrhea, and positive test for occult blood in stool.

Genitourinary: Urinary frequency (2 to 6%); and rarely, enuresis, urinary retention, dysuria, impotence, inability to ejaculate, nocturia, hematuria.

A dose-related increase in incidence of ovarian cysts and a less marked increase in enlarged and/or hemorrhagic adrenal glands was observed in female rats treated chronically with baclofen.

Each tablet, for oral administration, contains 10 mg or 20 mg Baclofen.


7.16.2018 | Samantha Jacobson

Baclofen USP is a muscle relaxant and antispastic, available as 10 mg and 20 mg tablets for oral administration. Its chemical name is 4-amino-3-(4-chlorophenyl)-butanoic acid. Baclofen USP is a white to off-white, odorless or practically odorless crystalline powder. It is slightly soluble in water, very slightly soluble in.

Baclofen is useful for the alleviation of signs and symptoms of spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and concomitant pain, clonus, and muscular rigidity.

Baclofen is not indicated in the treatment of skeletal muscle spasm resulting from rheumatic disorders.

Start therapy at a low dosage and increase gradually until optimum effect is achieved (usually between 40–80 mg daily). The determination of optimal dosage requires individual titration.

It is not known whether this drug is excreted in human milk.

Baclofen Oral Uses, Side Effects, Interactions, Pictures, Warnings

9.18.2018 | Samantha Jacobson

Uses. Baclofen is used to treat muscle spasms caused by certain conditions (such as multiple sclerosis, spinal cord injury/disease). It works by helping to relax the muscles.

What conditions does Baclofen treat?

l your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone ), alcohol, marijuana, drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), other muscle relaxants (such as carisoprodol, cyclobenzaprine ), or antihistamines (such as cetirizine, diphenhydramine ).

US residents can call their local poison control center at.


5.14.2018 | Samantha Jacobson

Baclofen, sold under the brand name Lioresal among others, is a medication used to treat spasticity. It serves as a central nervous system depressant and skeletal muscle relaxant. It is also used in topical creams to help with pain. Chemically it is a derivative of the neurotransmitter γ-aminobutyric acid (GABA). It is believed.

The half life of baclofen is roughly 2–4 hours and it therefore needs to be administered frequently throughout the day to control spasticity appropriay. Biotransformation is low and the drug is predominantly excreted unchanged by the kidneys. The drug is rapidly absorbed after oral administration and is widely distributed throughout the body.

Withdrawal symptoms are more likely if baclofen is used for long periods of time (more than a couple of months) and can occur from low or high doses. Discontinuation of baclofen can be associated with a withdrawal syndrome which resembles benzodiazepine withdrawal and alcohol withdrawal.

Baclofen, Lioresal, Gablofen Side Effects and Dosing

12.21.2018 | Andrew Bishop

Explains the medication baclofen (Lioresal, Kemstro), a drug used for treating symptoms of MS (multiple sclerosis) such as spasm of skeletal muscles that cause muscle clonus, rigidity, and pain.

Treatment options vary depending on the type and severity of symptoms. Medications may be prescribed to manage MS symptoms.

Baclofen should be stored between 15 C (59 F) and 30 C (86 F).

What is baclofen, and how does it work (mechanism of action)?

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Pain that originates in the face is referred to as trigeminal neuralgia. This pain may be caused by: an injury, an infection.

Understanding Multiple Sclerosis Slideshow.

Based on the response, the dose can be increased by 5 mg every three days to a maximum of 80 mg/day in divided doses.